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21 days to design the best antibody candidates

Better, faster & safer therapeutic antibody discovery. We are changing the process with AI-based solutions

Discover

How do we define the best lead candidate?

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Binding to a selected epitope with high affinity

AI-based docking and affinity prediction allow us to design antibodies on predetermined epitopes, chosen to trigger the desired biological effect, and high efficacy.

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No cross-reactivity, but cross-specificity

We evaluate inter-molecular (off-targets) and inter-species reactivity, in order to limit the side effects (cross-reactivity) and anticipate binding for pre-clinical development (cross-specificity).

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Optimal manufacturability

Antibodies sequences liabilities (PTMs, aggregation motifs...) are evaluated during the molecular design, to optimize stability and limit immunogenicity.

Straight-line solution

Get fully characterized, high-affinity and epitope-specific humanized antibodies against your target in 21 days.

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Widen your pipeline

Lead candidates design in 21 days allows you to strengthen, parallelize and multiply your discovery programs.

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Fail fast

Do not risk to spend months never finding a good lead. Know fast, retry fast and succeed fast!

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Save time and money

No back-and-forth optimization of your hits. Start immediately with the lead candidates that are ready for development.

It's all about people

Combining expertises is key: computational science, biology and software development are essential skills at MAbSilico

Get to know the team
Vincent Puard
CEO

Vincent holds a PhD in biology and worked in biotech and public research institutes in Europe before founding MAbSilico.

Teamed up with Raouf, Saheli, Adrien & Sylvine
Teamed up with Zakaria
Teamed up with Mélanie & Yannick
Teamed up with Augustin, Yann & Christophe
Thomas Bourquard
CSO

Thomas holds a PhD in structural biology and computer sciences. He worked on implementing AI approaches in genomics, docking, immuno-oncology.

Teamed up with Raouf, Saheli, Adrien & Sylvine
Teamed up with Zakaria
Teamed up with Mélanie & Yannick
Teamed up with Augustin, Yann & Christophe
Astrid Musnier
Head of Biology

Astrid holds a PhD in cellular biology. She worked on GPCRs mechanisms of action and their modulation by antibodies.

Teamed up with Raouf, Saheli, Adrien & Sylvine
Teamed up with Zakaria
Teamed up with Mélanie & Yannick
Teamed up with Augustin, Yann & Christophe
Anne Poupon
CTO

Anne holds a PhD in Biomathematics. She's been working on protein-protein interactions at CNRS for more than 20 years.

Teamed up with Raouf, Saheli, Adrien & Sylvine
Teamed up with Zakaria
Teamed up with Mélanie & Yannick
Teamed up with Augustin, Yann & Christophe

Get in touch !

Drop us a line if you want to know more about our technology or if you are willing to talk about your projects. We are always keen on discussing science!

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Get the latest news !

Science
MAbSilico at AET form June 6 to 8.
May 30, 2023
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Business
MAbSilico at the BIO conference in Boston, June 5-8!
May 26, 2023
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Business
MAbSilico at PEGS!
May 8, 2023
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Science
Deciphering cross-reactivity. Read our new published paper !
August 26, 2022
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Science
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
June 27, 2022
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